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ScienceSoftware :: Bioinformatics :: Genetics :: Beacon Designer 7

Beacon Designer 7 #305

Beacon Designer: A comprehensive software for qPCR assays

Automate your real time PCR primer and probe design
Beacon Designer helps design successful SYBR® Green, TaqMan®, LNA™ spiked TaqMan®, TaqMan® probes for MethyLight assays, molecular beacon for both standard and NASBA® assays, Scorpions® and FRET assays by interpreting BLAST results for specificity and locating oligos avoiding template structures.

NEW: World wide release of version 7 of Beacon Designer with support for Scorpions® assays, making it the only product to include comprehensive support for all the popular qPCR chemistries.

Complete Features List	Feature Details
Highlights & Applications	Primers Probes

Beacon Designer™ automates the design of real time primers and probes. It is used by molecular biologists worldwide to design successful real time PCR assays. It saves the time and the money involved in failed experiments. Beacon Designer™ is a flexible solution to your real time primer and probe design needs and pays for itself many times over. As one of our esteemed customers says:

"We love this program - it has saved time in that we don't have to use 3 or 4 different programs to determine how well the probes we have designed will bind to other sequences. And it has saved money because I don't have to purchase several expensive labeled probes to test which one will work the best." - Dr. Gale Newman, Dept. Micro, Biochem, Immuno Morehouse School of Medicine, Atlanta, GA

Specific and Efficient Design: How Beacon Designer™ Makes it Possible?
You can BLAST search sequences and search for template structures from within the program. The results of both these searches are used while designing primers and probes. The regions that exhibit significant cross homologies and template structures are avoided automatically during the design.

Design Options Available

SYBR® Green Assay Design
SYBR® Green is perhaps the most commonly used real time PCR chemistry. Beacon Designer™ designs SYBR® Green PCR primers and helps you evaluate pre-designed SYBR® Green PCR primer sets. You have complete control over the design parameters or you can use the default values, chosen after considerable research and communication with experts.

Dual Labeled Probe Design
Beacon Designer™ currently supports four probe based chemistries:

TaqMan® Probes
Use Beacon Designer™ for optimal TaqMan® probes that help you study the differential gene expression or study SNP (single nucleotide polymorphisms) using TaqMan® SNP genotyping assays. You can also choose to design the increasingly popular Locked Nucleic Acid (LNA™) substituted TaqMan® probes, which are more stable than standard TaqMan® probes. To study DNA methylation, Beacon Designer™ helps design primers and TaqMan® probes for MethyLight assays. MethyLight is a high throughput assay used to discriminate between methylated and unmethylated DNA. Using Beacon Designer™, you can design suitable control primers and probes by designing oligos for the methylated and the unmethylated strands, and for the untreated DNA sequence. With any of these chemistries, you could evaluate a pre-designed/published primers or TaqMan® probes. The design results are reported in a ranked order, giving you a list of alternates to choose from. Depending on the oligo properties, a rating is assigned. Please read the Rating section in the online help for details.

Molecular Beacons
Design or evaluate standard molecular beacons or molecular beacons for NASBA® assays. NASBA® is a primer-dependent technology that can be used for the continuous amplification of nucleic acids in a single mixture at one temperature. You can now design molecular beacons for NASBA® assays for single template or multiplex reactions.

Scorpions®
Beacon Designer™ supports the design of Scorpions® primers and probes. Scorpions® assays are important in that they are independent of the enzymatic cleavage of the probe. The primer and probe element are physically coupled during the reaction. Read more about the Scorpions® technology.

FRET Probes
Beacon Designer™ supports design and evaluation of pre-designed FRET probes. FRET probes that are compatible with pre-designed SYBR® Green primers can be designed in Beacon Designer™.

Multiplex Real Time PCR Assays
With Beacon Designer™ you can design TaqMan® based multiplex real time PCR assays for upto four sequences including reference gene selection. Read more.

Beacon Designer™ complete feature list >> click here.

Please browse through the Feature List of Beacon Designer™ below to learn more about what the program can do for you.

Beacon Designer™ Features

Beacon Designer™ Highlights

Beacon Designer™ Applications

Real Time PCR Primer Design	MethyLight Assays	Real Time PCR
SYBR® Green Primer Design	Scorpions® Assays	DNA Methylation
TaqMan® Probe Design	LNA™ Substituted TaqMan® Assays
Molecular Beacon Design	NASBA Assays
FRET probe design	Multiplex Real Time PCR
Database Support
Input & Output Formats

If you are interested to check out Beacon Designer's functions by yourself, download a
Demo Version of Beacon Designer here:

Demo for Windows

Demo for Mac

System Requirements

For Windows

Required

Recommended

CPU	Pentium III	Pentium IV
RAM	256 MB of available RAM	512 MB of available RAM
Hard Disk Drive Space	500 MB of available hard disk	1 GB of available hard disk
Screen Resolution	800 X 600	1024 X 768

Platforms supported for Windows: 98/2000/ME/XP/Vista/Windows 7

For Power PC

Required

Recommended

CPU	iMac Power PC G3 350	iMac Power PC G3 350
RAM	256 MB of available RAM	512 MB of available RAM
Hard Disk Drive Space	500 MB of available hard disk	1 GB of available hard disk
Screen Resolution	800 X 600	1024 X 768

For Intel®-based Mac

Required

Recommended

CPU	Intel 1.8 GHz Intel Core Duo	Intel 1.8 GHz Intel Core Duo
RAM	256 MB of available RAM	512 MB of available RAM
Hard Disk Drive Space	500 MB of available hard disk	1 GB of available hard disk
Screen Resolution	1440 x 900	1440 x 900

Pricing

Beacon Designer Pricing & Packages

License Type	Commercial	Academic
Single User License	$ 2.985,00 $ 2.835,75	Contact Us!
4 thru 9 User License	Contact Us!	Under Request
10 thru 100 User License	Contact Us!	Under Request
Competitive Upgrade	Contact Us!	Under Request

NOTE: If you want to purchase Academic License(s) or <3 Licenses with Volume Discount please contact us!

Details

Price: $2,835.75 (€ 2,552.18)

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